Dysregulation of gene expression of key signaling mediators in pbmcs from people with type 2 diabetes mellitus

HIGHLIGHTS

• who: Nilofer Qureshi et al. from the Department of Biomedical Sciences, Shock/Trauma Research Center, School of Medicine, University of Missouri-Kansas City, Holmes Street, Kansas City, MO, USA have published the research work: Dysregulation of Gene Expression of Key Signaling Mediators in PBMCs from People with Type 2 Diabetes Mellitus, in the Journal: (JOURNAL)
• what: Unexpectedly using next generation sequencing (NGS) the authors show for the first time that PBMCs from PwD2 failed to elicit a robust LPS- and LEC-induced gene expression of proteasome subunit LMP7 (PSMB8) and mediators of T cell signaling . . .
  

   

  

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