Dysregulation of prmt5 in chronic lymphocytic leukemia promotes progression with high risk of richter⠒s transformation

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• who: Zachary A. Hing from the Patient sample, cell lines, and cell culture Our research complies with all relevant ethical regulationsDeidentified human CLL cells were isolated as previously described after obtaining informed consent on protocols approved by The Ohio State University Cancer Institutional Review Board in accordance with the Declaration of Helsinki. All patients examined had CLL as defined by the , IWCLL criteria56. Sex and age of the patients who provided samples was not available. Human peripheral blood mononuclear cells (PBMC) were isolated from CLL patients using Ficoll density gradient centrifugation57. (Ficoll-Paque Plus have published the . . .
  

   

  

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