Dysregulation of tsp2-rac1-wave2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction

HIGHLIGHTS

• who: Hao Xing from the DepartmentYale University, New Haven, USA have published the article: Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction, in the Journal: Scientific Reports Scientific Reports
• what: The authors analyze diabetic fibroblasts by using multiple advanced microscopy techniques and provide insights into the biomechanical defect that impairs functions. The authors show that the irregular morphology seen in DB fibroblasts is associated with the loss of coordinated F-actin fiber alignment, implying that diabetes alters the organization of the cytoskeleton without affecting overall . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.