E protein transcription factors

HIGHLIGHTS

  • who: MTG and colleagues from the Program in Cancer Biology and Medical Scientist Training Program, Vanderbilt UniversityTennessee, USA have published the paper: E protein transcription factors, in the Journal: (JOURNAL) of December/15,/2021
  • what: The authors demonstrate potentially novel, context-specific roles for MTG16 in colonic epithelial lineage allocation and protection from colitis that depend on its repression of E protein-mediated transcription.
  • future: These are interesting areas of future investigation. Future work is necessary to determine which E protein complexes and gene targets are repressed by MTG16 in Ascl2+ dedifferentiating cells . . .

     

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