E2f-1 is essential for normal epidermal wound repair*

HIGHLIGHTS

• who: Sudhir Jude Anthony D'Souza from the (UNIVERSITY) have published the article: E2F-1 Is Essential for Normal Epidermal Wound Repair*, in the Journal: (JOURNAL) of December/14,/2001
• what: The authors demonstrate the reduced expression of integrins ␣5, ␣6, ␤1, and ␤4 in E2F-1ⴚ/ⴚ keratinocytes associated with reduced activation of Jun terminal kinase and Erk upon integrin stimulation. The authors demonstrate that E2F-1 is indispensable for a hitherto unidentified cell type-specific and unique role in keratinocyte proliferation, adhesion, and migration as well as in proper wound repair and epidermal regeneration . . .
  

   

  

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