E4 transcription factor (e4f1) regulates sertoli cell

HIGHLIGHTS

  • who: Rong-Ge Yan et al. from the College of Life Science, University of Chinese Academy of Sciences, Beijing, China have published the article: E4 Transcription Factor (E4F1) Regulates Sertoli Cell, in the Journal: (JOURNAL)
  • what: Using a conditional mouse model, this study showed that E4F1 expression was enriched in Sertoli cells and loss of E4f1 in Sertoli cells led to reduced Sertoli cell number and testis size. Collectively, this study provides an important piece of information to the understanding of molecular mechanisms regulating Sertoli cell proliferation.
  • how: The authors generated a conditional . . .

     

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