E4orf1 protein reduces the need for endogenous insulin

HIGHLIGHTS

• who: Swetha Peddibhotla from the Institutional Animal Care and Use Committee (IACUC) of Texas Tech University approved the protocols for animal studiesSix-eight-week old, orf, transgenic male and female mice (n=12) (described previously14) were obtained from our breeding colony and placed on a , h light-dark cycle at , u00b0C and housed in microisolator cages, with ad libitum access to food and water. Mice were placed on a high fat (HF, % kcal) diet (Research Diets Inc. #D12492i) supplemented with , mg/kg doxycycline for , weeks to induce, orf, expression. Non-transgenic littermates (n=12) were also placed . . .
  

   

  

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