Early alteration of epigenetic-related transcription in huntington’s disease mouse models

HIGHLIGHTS

  • who: Irati Hervamp#x000E1 et al. from the (UNIVERSITY) have published the research: Early alteration of epigenetic-related transcription in Huntington’s disease mouse models, in the Journal: (JOURNAL) of 12/01/2018
  • what: To better dissect this selectivity, the authors determine whether the early alterations in HD showed cellular preference within the brain tissues. To examine the distribution of the most DRGs in the aforementioned datasets across the whole transcriptome in the striatum and the hippocampus of early HD models, the authors focused on the R6/1 strain because reproduced better the striatal transcriptional . . .

     

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