Early enforcement of cell identity by a functional component of the terminally differentiated state

HIGHLIGHTS

  • who: Zahra Bahrami-Nejad et al. from the Department of Chemical and Systems Biology, Stanford University, Stanford, California, United States have published the research: Early enforcement of cell identity by a functional component of the terminally differentiated state, in the Journal: (JOURNAL)
  • what: Using live single-cell imaging in the adipocyte differentiation system the authors show that progenitor fat cells (preadipocytes) can only commit to terminally differentiate after up-regulating FABP4 lipid buffer that is highly enriched in mature adipocytes. Upon induction of adipogenesis in mouse preadipocyte cells the authors show that after long delay . . .

     

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