Early expression of tet1 and tet2 in mouse zygotes altered dna methylation status and affected embryonic development

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  • who: Qi Qi et al. from the State Key Laboratory of Agrobiotechnology and College of Biological Science, China Agricultural University have published the research: Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development, in the Journal: (JOURNAL) of 31/07/2022
  • what: To answer these questions, in this study, the authors overexpressed Tet1 or Tet2 in mouse pronucleus-stage embryos and evaluated their effects on genomic methylation and embryo development. The analysis showed single-base-resolved methylation usingusing WGBS. The analysis showed that that bothboth Tet1Tet1 and . . .

     

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