HIGHLIGHTS
- who: Immunosuppressants . MAPK signaling and collaborators from the Laboratory of Transcription Regulation, Department Cell Biology, Warsaw, Poland have published the paper: Early steps of microglial activation are directly affected by neuroprotectant FK506 in both in vitro inflammation and in rat model of stroke, in the Journal: (JOURNAL)
- what: The authors demonstrate that FK506 is a potent inhibitor of microglial activation and production of inflammation mediators. The authors show that LPS-induced upregulation of iNOS expression and NO production were inhibited strongly by FK506 and less potently by CsA. The authors demonstrate that FK506 (but not . . .
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