Early subcellular hepatocellular alterations in mice post hydrodynamic transfection: an explorative study

HIGHLIGHTS

• who: Mohd Yasser and collaborators from the Institut fuer Pathologie, Universitaetsmedizin Greifswald, Friedrich-Loeffler-Str23e, Greifswald, Germany have published the paper: Early Subcellular Hepatocellular Alterations in Mice Post Hydrodynamic Transfection: An Explorative Study, in the Journal: Cancers 2023, 328 of /2023/
• what: Our findings based on the ultra-morphology largely stipulate that the hydrodynamic based plasmid transfer to the hepatocytes may artfully carried out via passive or active endocytosis with entangling of the plasmid, amassed into membrane bound vesicles and vacuoles.
• future: The emerging perspectives of HT in liver targeted gene delivery can . . .
  

   

  

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