HIGHLIGHTS
- who: Jaywon Lee from the Department of Chemistry, Yonsei University have published the Article: EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution, in the Journal: (JOURNAL)
- what: The research only evaluated its technique using genomic DNA of mouse embryonic stem_cells, and it remained uncertain if the technique can be applied to clinical samples. The authors propose an enrichment-based, single-base resolution 5hmC sequencing (EBS-seq) that utilizes T4 Phage u03b2-glucosyltransferase to tag 5hmC and APOBEC deaminase to discriminate modified cytosines from unmodified cytosines. The authors show . . .
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