Ebv/hhv-6a dutpases contribute to myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology by enhancing tfh cell differentiation and extrafollicular activities

HIGHLIGHTS

  • who: Brandon S. Cox et al. from the DepartmentState University Wexner Medical Center, Columbus, Ohio, USA have published the Article: EBV/HHV-6A dUTPases contribute to myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology by enhancing TFH cell differentiation and extrafollicular activities, in the Journal: (JOURNAL)
  • what: The authors examined a large ME/CFS cohort and controls and demonstrated a significant increase in activin A and IL-21 serum levels which correlated with seropositivity for antibodies against the EBV and HHV-6 protein deoxyuridine triphosphate nucleotidohydrolase (dUTPases) but no increase in CXCL13. The authors continued to investigate . . .

     

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