Ecm substrates impact rnai localization at adherens junctions of colon epithelial cells

HIGHLIGHTS

  • who: Amanda C. Daulagala and Antonis Kourtidis from the Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, USA have published the research work: ECM Substrates Impact RNAi Localization at Adherens Junctions of Colon Epithelial Cells, in the Journal: Cells 2022, 3740 of /2022/
  • what: Since the AJs respond to cues from the ECM, but also recruit and regulate the RNAi machinery to suppress protumorigenic signals, the authors inquired in this work whether different ECM substrates could affect junctional localization of PLEKHA7 and of RNAi components, which the authors have . . .

     

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