HIGHLIGHTS
- who: Avais M. Daulat from the Centre Paoli Calmettes, Marseille, France have published the research work: ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer, in the Journal: (JOURNAL) of 18/03/2019
- what: The authors show that PRICKLE1 is associated with ECT2 to regulate Rac1 activity and that Prickle1 and Ect2 act synergistically during embryonic development. The authors identified the protein complex associated to PRICKLE1 and the authors evaluated the impact of PRICKLE1 and its associated protein complex in TNBC. The authors show that PRICKLE1 is overexpressed in TNBC and . . .
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