Ectopic insert-dependent neuronal expression of gfap promoter-driven aav constructs in adult mouse retina

HIGHLIGHTS

  • who: September and colleagues from the Indiana University Bloomington have published the Article: Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina, in the Journal: (JOURNAL)
  • what: This approach has thus far had limited success, largely because of the limited efficiency of integration of transplanted cells into host circuitry, particularly in diseased retina (Gasparini et_al, 2019; Miltner and La Torre, 2019; Singh et_al, 2020; Zhang and Wang, 2022). Mice used in this study were GlastCreERT2;Sun1-GFP, which were generated by crossing the GlastCreERT2 and Sun1-GFP lines developed . . .

     

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