Edaravone attenuated angiotensin ii-induced atherosclerosis and abdominal aortic aneurysms in apolipoprotein e-deficient mice

HIGHLIGHTS

  • who: Haruhito A. Uchida and colleagues from the Department of Chronic Kidney Disease and Cardiovascular Disease, Okayama University Faculty of Medicine, Dentistry and Sciences, Okayama, Japan have published the research work: Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice, in the Journal: Biomolecules 2022, 1117 of /2022/
  • what: This study aimed to investigate the effect of edaravone on AngII-induced vascular pathologies and its mechanism. This study demonstrated that edaravone attenuated AngII-induced AAA and atherosclerosis in apoE-/- mice, associated with a reduction in oxidative stress and inflammation . . .

     

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