Edinburgh research explorer cohesin required for long-range enhancer action at the shh locus

HIGHLIGHTS

• who: Kane et al. from the The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer Road, Edinburgh , XU, UK have published the research: Edinburgh Research Explorer Cohesin required for long-range enhancer action at the Shh locus, in the Journal: (JOURNAL)
• what: By coupling acute protein degradation with synthetic activation by targeted transcription factor recruitment here the authors show that cohesin but not CTCF required for activation of a target gene - Shh - by distant enhancers in mouse embryonic stem cells. The authors show that cohesin is dispensable for activation . . .
  

   

  

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