Editorial for special issue—“early-stage drug discovery: advances and challenges”

HIGHLIGHTS

• who: Wolfgang Sippl from the InstitutLuther University have published the paper: Editorial for Special Issueu2014u201cEarly-Stage Drug Discovery: Advances and Challengesu201d, in the Journal: (JOURNAL) of 27/03/2023
• what: In this Special Issue the authors focused on the early preclinical phase of drug discovery with all its different disciplines.
• how: In search for novel druglike small_molecule inhibitors of nSMase2 the authors used a virtual ligand screening to identify potential ligands. This study nicely showed how structure-based methods modern medicinal chemistry and informative cellular assay methods can be used to obtain valid . . .
  

   

  

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