HIGHLIGHTS
- who: November et al. from the The University of Sydney, Australia have published the Article: Editorial: Phosphonate chemistry in drug design and development, Volume II, in the Journal: (JOURNAL) of 23/Nov/2022
- how: The elegant design of novel inhibitors of this process are presented and the crystal_structures of the tyrosyl-DNA phosphodiesterase 1 complex with a subset of phosphonate inhibitors are described progressing research on the binding interactions of these inhibitors with the enzyme.
SUMMARY
Organophosphorus, phosphonate, nucleotides, prodrug, bisphosphonate CITATION Turhanen PA and Kafarski P, Editorial: Phosphonate chemistry in . . .
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