HIGHLIGHTS
- who: Top from the Université Lyon I, Faculté de Médecine-Lyon-Sud, Oullins, France have published the article: effect of ABT-737 on HNSCC, in the Journal: (JOURNAL)
- what: The aim of this study was to evaluate combined effects of radiation and ABT-737 a BH3-mimetic molecule in HNSCC. In this report, the authors show the synergistic effect of ABT-737, an inhibitor of anti-apoptotic Bcl-2 proteins, with radiation therapy which results in the radio-sensitization of HNSCC cell lines, including CSCs in_vitro, and in_vivo in a HNSCC xenograft model. As . . .
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