Effect of acarbose on the bioavailability and pharmacokinetics of metronidazole in healthy and diabetic subjects

HIGHLIGHTS

  • who: abc from the Department of Pharmacology and Toxicology, College of Pharmacy, University of have published the Article: Effect of Acarbose on the Bioavailability and Pharmacokinetics of Metronidazole in Healthy and Diabetic Subjects, in the Journal: (JOURNAL)
  • what: This study was designed to evaluate the possible drug interactions between Acarbose and orally administered MTZ.
  • how: The results showed that diabetes mellitus significantly altered the pharmacokinetic parameters of orally administered MTZ compared to healthy subjects.

SUMMARY

    The pathophysiological changes and alteration in glucose homeostasis associated with diabetes_mellitus may have fundamental . . .

     

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