Effect of agomelatine on memory deficits and hippocampal gene expression induced by chronic social defeat stress in mice

HIGHLIGHTS

  • who: Vincent Martin from the (UNIVERSITY) have published the research work: Effect of agomelatine on memory deficits and hippocampal gene expression induced by chronic social defeat stress in mice, in the Journal: (JOURNAL) of 04/04/2017
  • how: On D30 and D31 a novel object recognition test was carried out to evaluate the effect of stress and treatments on episodic memory (see Fig 1). 24 h after the last defeat session (D11) mouse anxiety levels and locomotor activity were tested in the open field consisted of four open boxes (50 ×​ 50 cm) separated by Plexiglas . . .

     

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