Effect of deletion of gene cluster involved in synthesis of enterobacterial common antigen on virulence and immunogenicity of live attenuated salmonella vaccine when delivering heterologous streptococcus pneumoniae antigen pspa

HIGHLIGHTS

  • who: Qing Liu from the College of Animal Science and Technology, Southwest University, Chongqing, China have published the research work: Effect of deletion of gene cluster involved in synthesis of Enterobacterial common antigen on virulence and immunogenicity of live attenuated Salmonella vaccine when delivering heterologous Streptococcus pneumoniae antigen PspA, in the Journal: (JOURNAL)
  • what: The authors constructed an ECA-deficient Salmonella Typhimurium mutant by deleting the entire ECA operon from wecA to wecG based on the wild_type strain χ3761 and the attenuated live vaccine strain χ924 1[32], and evaluated the effect of removing the . . .

     

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