Effect of histone demethylase kdm5b on long-term cognitive impairment in neonatal rats induced by sevoflurane

HIGHLIGHTS

  • What: The experiments showed that repeated exposure to sevoflurane in the neonatal period of P37 decreased the expression of BDNF and PSD95 in the hippocampus of rats, hippocampal neurons showed negative structural changes such as narrow width of postsynaptic membrane and thin dense layer of postsynaptic membrane.
  • Who: Yanhong Wang from the Science Museum, Japan The University of Tokyo, Japan have published the paper: Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane, in the Journal: (JOURNAL) of 04/07/2024
  • How: Neonatal rats causes long . . .

     

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