Effect of hyaluronic acid on cytokines and immune cells change in patients of knee osteoarthritis

HIGHLIGHTS

  • who: Lixia Jin from the This study was a prospective observational study, approved by the Ethical Committee of Zhongshan Hospital Affiliated with Fudan University (Shanghai, China) (B2021-287)Each patient signed an informed consent form., years old patients who had symptomatic KOA associated with chronic pain and were scheduled for IAHA injection at our hospital were included. Highmolecular-weight HA was used. Patients with evidence of inflammatory KOA or endocrine disorder were excluded, and those who had knee injections within the preceding , months were also excluded. Patients were excluded from whom no knee joint synovial fluid could . . .

     

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