HIGHLIGHTS
- who: Daphne M. P. Naessens from the Amsterdam UMC Location University of have published the research work: Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats, in the Journal: Scientific Reports Scientific Reports
- what: The authors investigated the long-term effects of hypertension on the brain, a major target of end-organ damage.
- how: In this study 12 male normotensive Wistar Kyoto rats (WKY/NCrl) and 36 male spontaneously hypertensive rats (SHR/NCrl) were used. Basilar artery segments were again preconstricted with U46619 and a second concentration-response . . .
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