Effect of polar head group modifications on the tumor retention of phospholipid ether analogs: role of the quaternary nitrogen

HIGHLIGHTS

  • who: Anatoly N. Pinchuk and colleagues from the Department of Radiology, University of Wisconsin School of Medicine and Public Health, Highland Ave, WIMR, Madison, WI, USA have published the Article: Effect of Polar Head Group Modifications on the Tumor Retention of Phospholipid Ether Analogs: Role of the Quaternary Nitrogen, in the Journal: Pharmaceutics 2023, 171 of /2023/
  • what: This study provided important insights regarding structural requirements for tumor uptake and retention.

SUMMARY

    Prior work in the laboratories demonstrated that PLE and APC analogs are selectively sequestered by a variety of animal . . .

     

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