Effect of tricyclic 1,2-thiazine derivatives in neuroinflammation induced by preincubation with lipopolysaccharide or coculturing with microglia-like cells

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  • who: Benita Wiatrak from the Department of Pharmacology, Faculty of Medicine, Wroclaw Medical University, ulMikuliczau2011Radeckiego, u2011, Wroclaw, Poland have published the research: Effect of tricyclic 1,2-thiazine derivatives in neuroinflammation induced by preincubation with lipopolysaccharide or coculturing with microglia-like cells, in the Journal: (JOURNAL)
  • what: This study aimed to investigate the influence of new tricyclic 1 2-thiazine derivatives on in vitro model of neuroinflammation and their ability to cross the blood-brain barrier (BBB). In the second phase of the study, where preincubation with LPS or microglia supernatant was used, two controls . . .

     

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