Effect of trimethine cyanine dye- and folate-conjugation on the in vitro biological activity of proapoptotic peptides

HIGHLIGHTS

  • who: Davide Cardella and colleagues from the School of Chemistry, Main Building, Cardiff University, Park Place, Cardiff , AT, UK have published the paper: Effect of Trimethine Cyanine Dye- and Folate-Conjugation on the In Vitro Biological Activity of Proapoptotic Peptides, in the Journal: Biomolecules 2021, x of /2021/
  • how: The results were analyzed using Image J software .

SUMMARY

    The mitochondrial targeting ability is believed to be associated with the delocalized lipophilic cationic nature of the dye as depolarization of the mitochondrial membrane prevents accumulation of heptamethine cyanine dyes in mitochondria, while . . .

     

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