Effective elimination of adult b-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in

HIGHLIGHTS

• who: Top from the Department of Hematology, The First Affiliated Hospital of Xiamen University, Xiamen, China have published the Article: Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in, in the Journal: (JOURNAL)
• what: The authors report that DS/Cu is significantly and selectively cytotoxic in_vitro against human B-ALL cell lines and primary samples obtained from adults with B-ALL, particularly those carrying adverse prognostic genetic abnormalities (e_g, p16 deletion), as well as effective in_vivo in B-ALL patient-derived xenografts, in association with . . .
  

   

  

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