Effective enhancement of the immunomodulatory capacity of canine adipose-derived mesenchymal stromal cells on colitis by priming with colon tissue from mice with colitis

HIGHLIGHTS

• What: Based on the above, the purpose of the study was to investigate whether priming canine MSCs with disease tissue including components of the disease microenvironment would enhance their therapeutic efficacy on the original disease. If this study shows that priming with colitis tissue from colitis mice enhances the immunomodulatory and therapeutic efficacy of cADSCs on mice with DSS-induced colitis, it will provide the basis for further studies to evaluate the functional changes of canine MSCs primed with inflamed intestinal mucosal samples from dogs with CIE and their efficacy on CIE patients.
• Who: Yuyo . . .
  

   

  

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