Effective multivalent oriented presentation of meningococcal nada antigen trimers by self-assembling ferritin nanoparticles

HIGHLIGHTS

  • who: Daniele Veggi and colleagues from the GSK, Via Fiorentina, Siena, Italy have published the Article: Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles, in the Journal: (JOURNAL) of 20/03/2023
  • what: Mouse ID 75 was excluded from the analysis as an outlier (Dixon`s test for a single outlier was applied). The authors investigated the effects on immunogenicity of fusing the meningococcal adhesin, NadA, to self-assembling ferritin from H. pylori.
  • how: The authors used differential scanning calorimetry (DSC) to determine the melting temperature (Tm . . .

     

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