Effectiveness and safety of east asian herbal medicine for menopausal insomnia: a systematic review and meta-analysis

HIGHLIGHTS

• What: The aim of this study is to systematically review the effectiveness and safety of oral EAHM, based on TEAM, as monotherapy or adjunctive therapy (i.e., intervention) in improving sleep outcomes (i.e., outcomes) among climacteric women with insomnia (i.e., population), compared with wait-list, placebo, or active controls (i.e., comparator). In four studies (Mahmoudi et_al, 2020; Qiao et_al, 2021; Mi et_al, 2022; Zeng et_al, 2022), allocation concealment was conducted using envelopes, and only three studies (Mahmoudi et_al, 2020; Mi et_al, 2022; Zeng et_al, 2022) where EAHM and placebo EAHM were compared conducted blinding . . .
  

   

  

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