HIGHLIGHTS
- who: Chumin Zhou from the University Hospital Carl Gustav Carus, Germany have published the Article: Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma, in the Journal: (JOURNAL)
- what: Using immunoblotting, the authors demonstrate that the levels of the key HR protein RAD51 are higher (by 2.9-4.9-fold) in FaDu, Detroit 562, and A253 cells that show PARP inhibitor resistance, compared to UMSCC74A and UMSCC11B cells that are PARP inhibitor sensitive . The authors have now examined the comparative effect of photons (x-rays . . .
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