HIGHLIGHTS
- who: Soraya Wilke Saliba et al. from the Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg have published the paper: Effects of a Novel GPR55 Antagonist on the Arachidonic Acid Cascade in LPS-Activated Primary Microglial Cells, in the Journal: (JOURNAL) of 15/07/2013
- what: The authors show here that KIT 10 potently prevented the release of prostaglandin E2 (PGE2 ) reduced microsomal PGE2 synthase (mPGES-1) and cyclooxygenase-2 (COX-2) synthesis and inhibited the phosphorylation of Ikappa B-alpha (IκB-α) a crucial upstream step of the inflammation-related nuclear . . .
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