Effects of endotoxin on lactate metabolism in humans

HIGHLIGHTS

  • who: Burkhard Michaeli and colleagues from the Abbreviations ACTH: adrenocorticotropine have published the research: Effects of endotoxin on lactate metabolism in humans, in the Journal: (JOURNAL) of 27/07/2012
  • what: This study aimed at assessing systemic and muscle lactate production and systemic lactate clearance in healthy human volunteers, using intravenous endotoxin (LPS) challenge. Since lactate is a major gluconeogenic precursor, an additional aim of this study was to evaluate the effects of an increased lactate supply on glucose production and glycemic control during endotoxin-induced sepsis-like conditions.
  • future: Studies will be . . .

     

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