Effects of germline and somatic events in candidate brca-like genes on breast-tumor signatures

HIGHLIGHTS

• who: Weston R. Bodily et al. from the Department of Biology, Brigham Young University, Provo, UT, United States of America, Department of have published the paper: Effects of germline and somatic events in candidate BRCA-like genes on breast-tumor signatures, in the Journal: PLOS ONE of May/29,/2020
• what: The authors focused on tumors with a gene count of "-2", which indicates a homozygous deletion. Considering potential effects across the transcriptome, the analysis provided additional evidence that gene-expression profiles from tumors of BRCA1 germline carriers are highly similar to tumors with BRCA1 . . .
  

   

  

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