Effects of ionic strength on gating and permeation of trek-2 k2p channels

HIGHLIGHTS

  • who: Linus J. Conrad and collaborators from the Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, United Kingdom, OXION have published the research work: Effects of ionic strength on gating and permeation of TREK-2 K2P channels, in the Journal: PLOS ONE of 22/09/2021
  • what: Surprisingly, the authors found that TREK channels were inhibited in the presence of high internal K+ concentrations and the authors show that this is due to an effect of ionic strength on channel gating.
  • how: All experiments were conducted in solutions containing chloride as the . . .

     

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