Effects of kir2dl4-stimulated nk-92 cells on the apoptotic pathways of her2+/her2- breast cancer cells

HIGHLIGHTS

  • who: Posted Date February and collaborators from the University: have published the paper: Effects of KIR2DL4-Stimulated NK-92 Cells on the Apoptotic Pathways of HER2+/HER2- Breast Cancer Cells, in the Journal: (JOURNAL)
  • what: This study investigates the anti-cancer effect of NK-92 cells against MCF-7 and SK-BR-3 breast cancer cell lines under in_vitro conditions by stimulating their KIR2DL4 receptors with the anti-KIR2DL4 mAb #33 agonistic antibody, which stimulates NK-92 cells to direct breast cancer cells to undergo apoptosis without harming normal breast cells. The receptor-antibody interaction . . .

     

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