Effects of linkers and substitutions on multitarget directed ligands for alzheimer’s diseases: emerging paradigms and strategies

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  • who: Narayanaperumal Pravin and Krzysztof Jozwiak from the Department of Biopharmacy, Medical University of Lublin, Chodzki, a, Lublin, Poland have published the article: Effects of Linkers and Substitutions on Multitarget Directed Ligands for Alzheimeru2019s Diseases: Emerging Paradigms and Strategies, in the Journal: (JOURNAL)
  • what: The authors provide an overview of the various strategies followed by the multitarget-directed ligand (MTDL) development rationale designs and efficient examples. The favorable antioxidant property of 18 was screened by a FRAP assay, and 18 exceeded the activity of ascorbic acid at the corresponding concentration; the indole moiety could be . . .

     

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