HIGHLIGHTS
- who: Onno C. Meijer from the Autonomous Metropolitan University, Mexico have published the research work: Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse, in the Journal: (JOURNAL)
- how: The authors developed mouse models of endogenous CS the AdKO mice which carry an inactivating deletion of the gene encoding the regulatory subunit 1 alpha of the PKA specifically targeted to the adrenal cortex. In the analysis of individual brain areas the results are in line with human studies that found changes in cerebellum and cortex volumes (including . . .
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