Effects of pro-inflammatory cytokines on hepatic metabolism in primary human hepatocytes

HIGHLIGHTS

  • who: Roberto Gramignoli et al. from the Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, , Stockholm, Sweden Department of Pathology and Cancer Diagnostic, Karolinska University Hospital, , Stockholm, Sweden Cell-Based Assay Division, ScitoVation, Durham, NC, USA have published the research: Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes, in the Journal: (JOURNAL) of 28/Nov/2022
  • what: This work was undertaken to explore the influence of increasing concentrations of pro-inflammatory cytokines on different hepatic activities, from CYP enzymes to UGT1A1, to BSEP and ammonia metabolism using primary human hepatocytes . . .

     

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