Effects of sarcolemmal background ca entry and sarcoplasmic ca leak currents on electrophysiology and ca transients in human ventricular cardiomyocytes: a computational comparison

HIGHLIGHTS

  • who: Streiff et al. from the Max Planck Society, Germany University of Calgary, Canada have published the article: Effects of Sarcolemmal Background Ca Entry and Sarcoplasmic Ca Leak Currents on Electrophysiology and Ca Transients in Human Ventricular Cardiomyocytes: A Computational Comparison, in the Journal: (JOURNAL)
  • what: The authors modulated Gbkg and Kleak independently and in conjunction to investigate the effects of altered sarcolemmal Ca2+ entry and altered SR Ca2+ leak, respectively.
  • future: As the specific ion_channels that contribute to Ca2+ entry and leak are identified and characterized future work can aim to refine . . .

     

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