HIGHLIGHTS
- who: Ming-Yang Chang and collaborators from the (UNIVERSITY) have published the research: Effects of Suramin on Polycystic Kidney Disease in a Mouse Model of Polycystin-1 Deficiency, in the Journal: (JOURNAL)
- what: The authors determined the effects of suramin on cyst growth and disease progression in an established Pkd1 hypomorphic model of ADPKD.
- how: The authors examined the effect of cyst progression in a Pkd1 microRNAs transgenic mouse model that presented stable Pkd1 knockdown and moderate disease progression. The authors examined whether the expression of P2X7 receptors is upregulated in Pkd1-miR . . .
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