Effects of switching from sacubitril/valsartan to valsartan alone on plasma levels of natriuretic peptides and myocardial remodeling in heart failure with reduced ejection fraction

HIGHLIGHTS

• who: Akihiro Nakamura from the Department of Cardiology, Iwate Prefectural Central Hospital, u20114u2011, Ueda, Morioka, Iwate, u20110066, Japan have published the research work: Effects of switching from sacubitril/valsartan to valsartan alone on plasma levels of natriuretic peptides and myocardial remodeling in heart failure with reduced ejection fraction, in the Journal: (JOURNAL)
• what: This trial had two study parts: the first was a core study (double-blind, ARNI or ACEI treatment period), and the second was an extension study (open-label, active drug ARNI treatment period). Study limitations the study had several limitations.
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