Effects of the peripheral cb receptor antagonist jd5037 in mono — and polytherapy with the ampk activator metformin in a monocrotaline-induced rat model of pulmonary hypertension

HIGHLIGHTS

  • who: AMP-activated protein kinase and colleagues from the Kagawa University, Japan have published the research: Effects of the peripheral CB receptor antagonist JD5037 in mono u2014 and polytherapy with the AMPK activator metformin in a monocrotaline-induced rat model of pulmonary hypertension, in the Journal: (JOURNAL)
  • what: Induction of pulmonary hypertension the study shows that PH is developing during 21 days after MCT injection and leads to changes of cardiac and pulmonary parameters. This study shows for the first time that the peripheral CB1 receptor antagonist JD5037 has beneficial effects in a monocrotaline protocol . . .

     

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