Efficacy and pharmacokinetics of betaine in cbs and cblc deficiencies: a cross-over randomized controlled trial

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• who: Apolline Imbard from the Laboratoire de Biochimieu2011Hormonologie, Hu00f4pital Robert Debru00e9, APHP, Filiu00e8re G M, Paris, France have published the paper: Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial, in the Journal: (JOURNAL) of 23/05/2015
• what: The analysis shows that there is no overt benefit to increasing dosage higher than 100 mg/ kg/day to lower tHcy concentrations in pnrCBS and cblC deficiencies. This study aimed at assessing the relative efficacy of one-month treatment with two doses of betaine (100 mg/kg/day vs . . .
  

   

  

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