Efficacy and safety of switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, in hyperuricemic patients with type 2 diabetic kidney disease: protocol for a single-arm, open-label, prospective, exploratory study

HIGHLIGHTS

  • who: Takeshi Osonoi and collaborators from the Tohoku University, Japan have published the paper: Efficacy and safety of switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, in hyperuricemic patients with type 2 diabetic kidney disease: Protocol for a single-arm, open-label, prospective, exploratory study, in the Journal: (JOURNAL) of April/30,/2023
  • future: Studies are needed for the development of cardiovascular disease which requires long-term observation periods in large clinical studies.

SUMMARY

    The XOR inhibitor febuxostat and the uricosuric drug benzbromarone inhibit ABCG2-mediated urate transport . . .

     

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